Towards simulation of germinal matrix hemorrhage as a complication of premature birth
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چکیده
منابع مشابه
Towards simulation of germinal matrix hemorrhage as a complication of premature birth
The germinal matrix being an accumulation of immature blood vessels in the premature infant brain is known to be the main cause of the intracranial hemorrhage. To investigate the injuring mechanism to the blood vessels of the germinal matrix, a modeling scenario that consists of three basic steps is proposed. First, the cerebral blood flow that depends on autoregulation, CO2 reactivity, and var...
متن کاملRisk Factors of Germinal Matrix Intraventricular Hemorrhage in Premature Infants
OBJECTIVE To determine whether some clinical parameters can be used to predict the hemorrhage and whether the relationship between these clinical variables and the grades of hemorrhage is linear. METHODS A total of 230 premature infants, born at a gestational age less than 34 weeks were retrospectively reviewed. Germinal matrix-intraventricular hemorrhage (GM-IVH), the grade of the hemorrhage...
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Using the anterior fontanelle as an acoustic window, high resolution gray scale sonography brain scans with mobile apparatus were obtained in 35 premature infants. The sonographic technique provided accurate assessment of ventricular size and detected the subependymal germinal matrix and intraventricular hemorrhages. Ventricular size measurements correlated closely with computed tomography (CT)...
متن کاملGerminal matrix hemorrhage-intraventricular hemorrhage: pathogenesis and outcomes
Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) is one of the CNS injuries affecting preterm infants occurring in about 15%–20% of subjects weighing less than 1500 g. Currently, using ultrasonography, we recognize three grades of GMH-IVH. Grade I involving the subependymal parenchyma and/or extending in less than 10% of the ventricle, grade II with intraventricular bleeding not...
متن کاملPaucity of pericytes in germinal matrix vasculature of premature infants.
Germinal matrix (GM) is a richly vascularized collection of neuronal-glial precursor cells in the developing brain, which is selectively vulnerable to hemorrhage in premature infants. It has rapid angiogenesis associated with high levels of vascular endothelial growth factor (VEGF). Because pericytes provide structural stability to blood vessels, we asked whether pericytes were fewer in the GM ...
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ژورنال
عنوان ژورنال: Open Journal of Obstetrics and Gynecology
سال: 2013
ISSN: 2160-8792,2160-8806
DOI: 10.4236/ojog.2013.39a008